Alias Problem...
 

Under the Server General Tab I have the following in Apache Style Configurations:

Alias /phpMyAdmin /home/phpMyAdmin/
<Directory "/home/phpMyAdmin">
Options Indexes FollowSymLinks
DirectoryIndex index.php
Order allow,deny
Allow from all
</Directory>

Problem is, I keep getting 404's and I'm not sure what I'm doing wrong.

you probably need to configure it with native configuration if you use LSWS configuration instead of httpd.conf. Just add a static context instead.

you lost me but I am using LSWS to manage vhosts.

http://www.litespeedtech.com/docs/webserver/config/context/#generalContext

Is there an example of this somewhere? I've looked at that page and I'm still not sure how to do it.

Go to a vhost configuration, click context tab, add a context with type "General", set URI to "/phpMyAdmin/", location to "/home/phpMyAdmin/", save.
That's it.