v4.2.2, native litespeed server and vhost config.
seems like the same problem i get.
first of all the rewrite rules (joomla default rewrite rules):
RewriteEngine On
RewriteCond %{QUERY_STRING} base64_encode[^(]*\([^)]*\) [OR]
RewriteCond %{QUERY_STRING} (<|%3C)([^s]*s)+cript.*(>|%3E) [NC,OR]...